SCIENCE, HUMAN ANATOMY & HABITS, BIOLOGY & INNOVATION

Our hard-working science team and side by side cooperations with research institutions in Europe and Asia allow us to offer a variety of formulas from most scientifically tested products to all the way to new and most trendy all-natural ingredients. Our goal is to be always at the forefront of innovation in efficiency using newly discovered and ancient all-natural ingredients.

N-ACETYL CYSTEINE

Already one of the most popular treatments because it shows up in eggs, which tend to anchor the Sunday brunch many drinkers rely on, cysteine is an amino acid that helps your liver out. How Stuff Works explains it is "the substance that breaks down the hangover-causing toxin acetaldehyde in the liver's easily depleted glutathione." That means it can take some of the strain off your liver by helping to get rid of lingering toxins. And fear not, vegans and ovaphobes. Plenty of other foods contain cysteine, including poultry, oats, yoghurt, broccoli, red pepper, garlic, onions, brussels sprouts, wheat germ and dairy. 

It’s best to take NAC (at least 200 milligrams) as a “pre-tox” about 30 minutes prior to drinking to lessen alcohol’s toxic effects, which in turn, lessens your hangover the next day. However, it is actually harmful to take NAC after you drink, so if you forget to take these before you start sipping on martinis, do not make up for it when you get home. Another thing to note is the more drinks you have, the less effective NAC will be because as with most medications, it can only work up to a certain extent. But hey, if you can remember to take this supplement before going out, you will thank yourself in the morning.

The results of some animal studies suggest that NAC may decrease ethanol-induced hypertension and acetaldehyde levels in rats. Plus, it’s earned its reputation as a toxicity cure: NAC is used in hospital settings to treat Tylenol overdoses.

 

Publications:

https://clinicaltrials.gov/ct2/show/NCT02541422

https://www.cnbc.com/2018/12/31/bishop-stalls-hungover-how-to-cure-a-hangover.html

https://www.chatelaine.com/health/wellness/four-natural-hangover-cures-that-work/

https://link.springer.com/article/10.1007/BF02869573

https://www.nateliason.com/blog/prevent-hangovers

https://www.medscape.com/viewarticle/885865

https://en.wikipedia.org/wiki/Acetylcysteine

https://pdfs.semanticscholar.org/28aa/8f3c4fdceedb3a6eec5b80e744b71465167a.pdf

https://ichgcp.net/clinical-trials-registry/NCT02541422

https://www.theverge.com/2018/12/21/18151623/hang-over-cure-alcohol-science-health-shaughnessy-bishop-stall

https://www.newscientist.com/letter/mg20927980-300-hangover-chemistry/

VITAMIN C

Vitamin C is one of the most important vitamins for the hangover to consider. It is a strong antioxidant which supports a healthy immune system. Alcohol depletes ascorbic acid levels in the body. Replenishing its levels in the body helps protect the immune system, especially from the toxins that are introduced to the body by alcohol.

Ascorbic acid also helps speed up the metabolism of alcohol in the liver. These actions help alleviate hangover symptoms sooner. This makes it one of the best vitamins to prevent hangovers.

Vitamin C, or ascorbic acid, is known as a “scavenger antioxidant,” meaning its job is to soak up and neutralize cellular bad guys. For example, people use a Vitamin C shower filter because the Vitamin C absorbs and neutralizes all the chlorine and other crap in the water.

Most of us have heard the scurvy story: before Vitamin C was discovered, sailors braving long voyages without access to fresh fruits or vegetables would develop a deficiency in the nutrient causing a nasty, painful death. A true pirate’s death, you could say.

Now Vitamin C is perhaps the most ubiquitous of all vitamins and its popularity isn’t just hype. The nutrient plays a crucial role in preventing heart disease, high blood pressure, cancer, osteoarthritis, and eye and gum deterioration.

Booze does a pretty good job of zapping the body’s store of needed minerals and Vitamin C is no exception. Even so, while alcohol depletes Vitamin C in body tissues, it can quickly be restored with Boozee Pre Drink.

Having a healthy dose of Vitamin C in your system before and after drinking may prevent or reduce the severity of hangovers by speeding up the metabolism of alcohol by the liver. Alcoholics may also benefit from keeping up their Vitamin C intake as it can reduce alcohol cravings.

MAGNESIUM

Did you know magnesium supplementation is a great way to easy your hangover? Opting to Magnesium is a Good Place to Start.

Magnesium aids your nerves and muscles work correctly by balancing the calcium within your body. Probably, the majority of people are deficient of it without even knowing it. It is not until you include the supplement to your regular regiment and keep good levels of magnesium that you understand the amazing benefits of it.

Magnesium can help cure PMS and help you get rid of that morning hangover. Still not satisfied?

In case you didn’t know yet, alcohol is a diuretic. That means, it causes you to excrete fluids at a fast pace. As you are doing all that peeing, one of the vital minerals which leave your body at a very alarming rate is magnesium. Magnesium is a mineral your bodies require for more than 300 biochemical reactions.

Magnesium also supports muscle and nerve function keeps the immune system tough and controls your heartbeat. Alcohol depletes magnesium, resulting in a possible deficiency. The risk increases with how much alcohol you drink.

Why Intoxication Activates Magnesium Deficiency?

People who drink too much alcohol are more likely to have poor diets. They also might not get the foods they require to reach their magnesium requirements. The National Institute on Alcohol Abuse and Alcoholism states that alcoholics might get as much as half of their calories from alcohol offering no nutrients at all.

What’s more, alcohol also negatively impacts digestion, usage, and store of nutrients. It lessens the discharge of pancreatic enzymes hence obstructing with the breakdown of nutrients into molecules your body can consume. Liquor also harms intestinal and stomach lining. That interferes or stops the absorption of nutrients into your bloodstream.

Nutritional magnesium stops platelet aggregation that helps to prevent the thickened blood and small clots which can cause blood vessel spasms as well as the pain of a hangover and headache.

Since alcohol is a diuretic, Magnesium will help you rehydrate, getting rid of that banging headache and dry mouth, making you feel a little more rejuvenated. Scientists have also suggested that magnesium can help to break down the alcohol left in your body, helping you to kick that hangover feeling faster.

MILK THISTLE

Milk thistle is a European thistle with a single purple flower in the centre and pointed leaves, it's known as a common weed.

The plant, if left alone can reach up to five feet in height. 

Milk Thistle is a popular herbal remedy for a hangover due to its long history of having been taken to help protect the liver from damage. It can be taken as tablets both before and after your night out.

A traditional herbal medicinal herb used to relieve the symptoms associated with occasional over indulgence of drink and food such as indigestion and upset stomach, exclusively based upon long-standing use as a traditional remedy.

People have taken milk thistle (Silybum marianum) for liver disorders, such as hepatitis and cirrhosis, since the days of the Ancient Greeks. The main active ingredient is an antioxidant called silybin. Studies suggest that silybin may help to protect the liver from alcohol damage by, for instance, reducing the effect of damaging molecules called ‘reactive oxygen species’, levels of which are boosted by alcohol.

It’s this plant active that’s been most thoroughly studied and is in the main responsible for milk thistle’s growing stature as a natural hangover soother, among other roles. It enhances antioxidant activity in the body and has been shown to have a protective, regenerative effect on liver cells. Alcohol, in particular, puts a strain on these cells, so milk thistle can help to minimise damage and allow cells to function better. Milk thistle’s anti-inflammatory properties could also help to negate some of the free-radical damage associated with alcohol and help the liver to metabolise toxins, but as far as so-called detoxing goes, your body is already equipped to break down alcohol over time.

Milk thistle handily starts making headlines around cold season as well as during the run of office parties, and for good reason according to nutritional therapist and founder of Wild Nutrition Henrietta Norton:

“Milk thistle is often seen as the post-party herb or one just for regular drinkers. While this can hold true, milk thistle also works to help the body clear unwanted chemicals that we come into contact with all the time from living in a modern world. Milk thistle is able to increase the level of one of the body's most powerful antioxidants, glutathione. Glutathione protects us (inside and out) from cellular damage, working to repair our system from the damage caused by pollution, infection, stress and inflammation.”

CORDYCEPS (REISHI)

The special bioactive compounds in cordyceps help improve circulation, allowing the body to utilize oxygen more efficiently. That means sustained energy, improved stamina (and libido), and quicker recovery from whatever you might have been doing, not to mention better sleep afterwards.

Traditionally been used as an anti-aging herb as well as using it for its ability to significantly improve the functioning of the immune system by acting as an immune modulator. It contains potent antioxidants and has a mild tranquilizing effect on the central nervous system. Ganoderic acids in Reishi inhibit histamine release, improve oxygen utilization and improve liver functions.

Ashok Kumar Panda and Kailash Chandra Swain wrote a study in 2011, published in the Journal of Ayurveda Integrative Medicine, noting that effects were initially noted by herders when their herds of goats, sheep and other animals consumed cordyceps while grazing and became much stronger and larger. Soon, locals were using it to increase milk production in cattle, as well as the cattle’s quality of life. These observations led to many practitioners to use cordyceps for a number of diseases that lead to wasting of muscle. The study found that local folk healers used the treatment for a total of 21 ailments, including bronchial asthma, bronchitis, tuberculosis, diabetes, common cold, cancer, erectile dysfunction and hepatitis, among others. The authors found a number of studies to support the positive reported effects. A lack of human study in clinically controlled environments was noted as a study limitation. 

In 1999, the Annual Meeting of the American College of Sports Medicine in Seattle released findings of a double-blind placebo controlled study. Among 30 elderly volunteers, cordyceps improved the amount of oxygen the participants were able to assimilate, by a significant amount. This may explain, in part, why much success has been reported among respiratory ailments.

In addition, as early as 1995, the Journal of Administration of Traditional Chinese Medicine found improvement among pulmonary ailments. Chronic obstructive pulmonary diseases improved 40% after administration of cordyceps.

In pneumonia, effects were more pronounced and significant based on a study done in Beijing in 1985. In the Collection on the Basic Medicinal and Clinical Studies of Submerged Culture, researchers noted a 400% improvement in mortality rates among patients with pneumonia who were administered cordyceps.

HOVENIA DULCIS

Hovenia dulcis (H. dulcis,more commonly known as the Japanese raisin tree) is a fruit tree of the Rhamnaceae family that has long been valued by practitioners of Eastern medicine.

The ripe fruits are edible raw or cooked and have a pear-like flavor. When dried, they look just like raisins. The fruit is sweet and can be used in candies or to make a honey substitute. It can also be made into juice or fermented to make wine and vinegar.

H. dulcis is native to Japan, China, North Korea, and South Korea and is also found growing naturally in the forests of Thailand and North Vietnam. Today it’s cultivated worldwide.

Traditional uses include:

  • treating hangovers

  • managing liver diseases

  • fighting parasitic infections

  • stabilizing blood sugar levels

H. dulcis has long been used in Korean and Chinese traditional medicine to relieve intoxication after excessive drinking. A detailed study, published in 1999, found that it lowers the blood alcohol level of mice. This suggests that H. dulcis could help people metabolize alcohol more quickly and efficiently, which could potentially relieve both drunkenness and hangovers.

Another study, published in 1997 in a Japanese medical journal, found that H. dulcis prevents alcohol-induced muscle relaxation in rats. This suggests that it could be used to combat the lack of coordination commonly associated with drunkenness.

There are no studies of these effects of H. dulcis on humans, but eating the fruit seems to be safe.

Studies suggest it prevents alcohol-related liver damage

H. dulcis and other herbal medicines have been used for hundreds of years in Chinese medicine to treat diseases of the liver. Research provides scientific proof that it really works, in mice:

  • Research in 2012 found that juice and fermented vinegar made from H. dulcis significantly reduced alcohol-related liver damage in mice. This suggests that adding H. dulcis to your diet could help protect your liver.

  • A 2010 study also found that a dose of H. dulcis could protect mice from alcohol-related liver damage. Researchers also noted an increase in antioxidant enzymes assisting in alcohol metabolism.

Taking herbs to protect the liver from toxic substances isn’t an invitation to drink more alcohol; if you or your health care provider have concerns about your liver health, avoid alcohol.

Many people have hangovers after they drink to the point of intoxication. The exact cause of hangovers is unknown, although there are most likely several contributing factors.

Typically, hangovers begin when the alcohol concentration in your blood begins to fall. Your hangover peaks when your blood alcohol level reaches zero. For many people, this hangover peak happens at right about the time they wake up in the morning.

Two enzymes — alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) — help your body break down alcohol. A 1999 study suggests that H. dulcis increases the activity of these enzymes, which means it could help you metabolize alcohol faster. Theoretically, the sooner your blood alcohol level reaches zero, the more quickly your hangover can pass.

A 2017 study found that people who ingested an extract of H. dulcis experienced less headache, dizziness, nausea, and weakness in their hangover than did others who did not take the extract.

However, there are many factors that contribute to a hangover that wouldn’t be affected by H. dulcis. This includes low blood sugar, dehydration, and gastrointestinal upset.

Drink fluids, rest, and consider having a couple of glasses of water between drinks next time.

Treats alcohol withdrawal syndrome

Some people believe that hangovers are partially caused by a sort of mini-withdrawal from alcohol. For people with alcoholism, however, alcohol withdrawal syndrome is a serious, even life-threatening condition. There are currently no prescription medications without significant side effects that can be used to treat alcohol withdrawal.

Research published in 2012 suggests that dihydromyricetin, a derivative of H. dulcis, has the potential to treat alcohol withdrawal syndrome. Research conducted with rats found a reduction in withdrawal symptoms including anxiety, tolerance, and seizures. Rats taking dihydromyricetin were also less likely to voluntarily consume alcohol, suggesting that it may also reduce alcohol cravings.

  • LinkedIn - Black Circle
  • Facebook
  • Youtube
  • Instagram

® 2019 Smart Drinking. All Rights Reserved. Smart Drinking ® Is a Registered Trademark